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14. Feb 12

Pim kinase inhibitors and ABT-737-induced apoptosi...

http://www.articlesbase.com/medicine-articles/pim-...

Pim serine/threonine kinases play critical roles in the development of human prostate cancer (PCa) and contribute to its therapeutic resistance. Overexpression of nuclear Pim-2 has been associated wit...

Volasertib in phase I clinical trials

http://www.articlesbase.com/medicine-articles/vola...

Polo-like kinases (Plks) are considered as the important regulators of the cell cycle, and contribute to the formation of and the changes in the mitotic spindle and the activation of CDK/cyclin comple...

16. Mar 12

Bortezomib - PubChem

http://pubchem.ncbi.nlm.nih.gov/summary/summary.cg...

Structure, classification, information, physical and chemical properties for Velcade, MG-341, PS-341, Bortezomib

13. Feb 17

The Background Of Dabigatran

https://en.wikipedia.org/wiki/Dabigatran

Our most significant finding is that lifestyle and HRQOL are associated in pre- and post-THA patients. There were differences between Japan and China in the indications for THA. Nearly half the Chines...

25. May 10

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von alek

Tanespimycin-Velcade Multiple Myeloma Trial Result...

http://www.myelomabeacon.com/news/2009/05/21/trial...

An abstract at the 2009 ASCO meeting describes a study on the combined effects of tanespimycin and Velcade (bortezomib) on patients with relapsed and refractory multiple myeloma.

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von alek

Tanespimycin-Velcade Combination Highly Effective ...

http://www.myelomabeacon.com/news/2009/12/14/tanes...

Summarizes several presentations at ASH 2009 about tanespimycin, a new drug currently being developed by Bristol-Myers Squibb and Kosan Biosciences. Tanespimycin inhibits Hsp90, which acts as a molecu...

24. Jun 10

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von alek

Panobinostat Combinations Show Therapeutic Benefit...

http://www.myelomabeacon.com/news/2010/06/23/panob...

Results of two Phase 1b clinical trials suggest that panobinostat in combination with Velcade (bortezomib) or Revlimid (lenalidomide) and dexamethasone (Decadron) is effective and well-tolerated in pa...

28. Jun 10

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von alek

Elotuzumab Combinations Show Encouraging Results I...

http://www.myelomabeacon.com/news/2010/06/21/elotu...

Preliminary results from two ongoing clinical trials suggest that elotuzumab in combination with either Velcade (bortezomib) or Revlimid (lenalidomide) plus ...

17. Apr 11

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von alek

Salubrinal

http://www.myelomabeacon.com/news/2009/04/07/addit...

Salubrinal is described in this article as having significant potential to improve the efficacy of Velcade when used to treat multiple myeloma patients.

05. Sep 11

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von alek

Subcutaneous Velcade for Multiple Myeloma

http://www.myelomabeacon.com/news/2011/09/02/subcu...

Detailed summary of subcutaneous Velcade (bortezomib) as a potential treatment for multiple myeloma patients. Includes comparison with intravenous Velcade and a comparison of clinical trial results w...

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